Patterns of vascular calcification in patients with end‐stage renal disease and calcific uremic arteriolopathy
نویسندگان
چکیده
Calcific uremic arteriolopathy or calciphylaxis is a rare and potentially fatal condition, which manifests as skin ischemia and necrosis, usually seen in patients with end-stage renal disease. It is frequently associated with vascular calcification visible on plain radiographs, which can occur in various patterns.
منابع مشابه
Calcific uremic arteriolopathy
Calcific uremic arteriolopathy (CUA)/calciphylaxis is an important cause of morbidity and mortality in patients with chronic kidney disease requiring renal replacement. Once thought to be rare, it is being increasingly recognized and reported on a global scale. The uremic milieu predisposes to multiple metabolic toxicities including increased levels of reactive oxygen species and inflammation. ...
متن کاملExtensive Skin Necrosis Ulcers and Systemic Vascular Insufficiency Syndrome with Calciphylaxis: A Case Report
Submit Manuscript | http://medcraveonline.com Calciphylaxis or calcific uremic arteriolopathy is a part of the continuum of systemic vascular and soft-tissue calcification that is common in end-stage renal disease (ESRD). The prevalence of vascular calcification among patients with CKD, especially those on dialysis, is reported to be more than 80% [1]. Coronary artery calcification leading to c...
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Calciphylaxis, or calcific uremic arteriolopathy, is a rare vascular disease that is seen in end stage renal disease and renal transplant patients; however, there are cases reported in literature with normal renal function but little systematic information is available on calciphylaxisfrom nonuremic causes. This article reviews the etio-pathogenesis, clinical features, laboratory abnormalities,...
متن کاملCalciphylaxis: Controversies in Pathogenesis, Diagnosis and Treatment.
Calcific uremic arteriolopathy, otherwise known as calciphylaxis, is a rare disease characterized by skin ulceration and tissue necrosis, likely the result of vascular calcification with accompanying intimal hypertrophy and small vessel thrombosis. Although most often associated with end-stage renal disease, it has also been seen in a number of other disorders (collectively referred to as nonur...
متن کاملVascular calcification in chronic renal failure.
The prevalence and extent of vascular calcification (VC) increases rapidly with time on dialysis. There is increasing evidence that medial calcification of conduit arteries, without intimal disease, is associated with important abnormalities of vascular compliance and increased risk of cardiovascular death. Coronary artery calcification is also common in end-stage renal disease, but further res...
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2017